Différences

Ci-dessous, les différences entre deux révisions de la page.

--- covid19:covid19-chloroquine [2020/07/15 18:34] – [Revue de presse thématique] Grégory Gutierez
+++ covid19:covid19-chloroquine [2020/08/24 00:14] – [Revue de presse thématique] Grégory Gutierez
@@ Ligne 52: / Ligne 52: @@
 ===== Revue de presse thématique =====
+^[[https://www.em-consulte.com/article/1382491/article/chloroquine-and-hydroxychloroquine-in-the-manageme|Chloroquine and hydroxychloroquine in the management of COVID-19: Much kerfuffle but little evidence]]^Thérapies^20/08/20^
+|The chloroquine hype, fueled by low-quality studies and media announcements, has yielded to the implementation of more than 150 studies worldwide. This represents a waste of resources and a loss of opportunity for other drugs to be properly evaluated. In the context of emergency, rigorous trials are more than ever needed in order to have, as soon as possible, reliable data on drugs that are possibly effective against the disease. Meanwhile, serious adverse drug reactions have been reported in patients with COVID-19 receiving hydroxychloroquine, justifying to limit its prescription, and to perform suitable cardiac and therapeutic drug monitoring.|||
+^[[https://presse.inserm.fr/une-etude-preclinique-montre-que-lhydroxychloroquine-na-pas-deffet-antiviral-contre-le-sars-cov-2-in-vivo/40346/|Une étude préclinique montre que l’hydroxychloroquine n’a pas d’effet antiviral contre le SARS-CoV-2 in vivo]]^Inserm^22/07/20^
+|L’étude montre donc que l’HCQ, qui possède des propriétés antivirales dans certains tests in vitro (à l’aide de cellules en culture), n’a pas d’efficacité antivirale in vivo chez le macaque dans les conditions spécifiques de ces travaux, et ce malgré une exposition pulmonaire importante.|||
 ^[[https://gizmodo.com/all-the-ways-the-influential-hydroxychloroquine-study-w-1844378680/amp|All the Ways the Influential Hydroxychloroquine Study Was Crap]]^Gizmodo^14/07/20^